As spring ends and summer begins here in Montana, we wanted to share another round of customer publications. It’s so important to us that our software plays a role in our client’s success, and we love to display the fruit of their hard efforts each month. Here are a few of the publication highlights:
- Bradley Aouizerat of UCSF and colleagues published Phenotypic and molecular characteristics associated with various domains of quality of life in oncology patients and their family caregivers in Quality of Life Research which used mixed modeling to identify latent classes of oncology patients over the course of radiation therapy to evaluate for genetic, demographic and clinical characteristics between these latent classes.
- In the Journal of Autoimmunity, Mauricio Arcos-Burgos of the Australian National University and colleagues published Definition of mutations in polyautoimmunity which sought to identify potentially autoimmune causative variants using WES data from extreme pedigrees segregating polyautoimmunity phenotypes.
- Australian Cattle Dogs with Neuronal Ceroid Lipofuscinosis are Homozygous for a CLN5 Nonsense Mutation Previously Identified in Border Collies was published in the Journal of Veterinary Internal Medicine by Ana Kolicheski of the University of Missouri and colleagues. The objective of the study was to characterize the Australian cattle dog form of neuronal ceroid lipfuscinosis using whole-exome sequencing.
- Rohan Palmer of Brown University and colleagues published Evidence of Shared Genome-Wide Additive Genetic Effects on Interpersonal Trauma Exposure and Generalized Vulnerability to Drug Dependence in a Population of Substance Users in the Journal of Traumatic Stress which raised the possibility that commonly occurring SNPs influence both the general tendency towards drug dependence and interpersonal trauma.
- Tabatha Cooper of the USDA, Heather Huson of Cornell University and several colleagues published Genomic evaluation, breed identification, and population structure of Guernsey cattle in North America, Great Britain, and the Isle of Guernsey in the Journal of Dairy Science in which twenty-one single nucleotide polymorphisms were identified for Guernsey breed determination and can be used in routine genotype quality control to confirm breed and identify crossbreeds.
- Genome-wide CNV analysis reveals variants associated with growth traits in Bos indicus was published in BMC Genomics by customer’s Lingyang Xu and Curtis Van Tassell of the USDA and colleagues. This study presents the first CNV-based GWAS of growth traits using high density SNP microarray data in cattle.