Category Archives: Customer success

Our Customers’ Success

         June 23, 2015

It is already almost halfway through 2015, and June has been especially busy as far as customer publication goes. We wanted to pass on the articles to you and congratulate our customers on their success!  Elena Gusareva and Kristel Van Steen of the University of Liege and colleagues recently published A cautionary note on the impact of protocol changes for genome-wide… Read more »

Recent Customer Publications

         May 12, 2015

Several of our customers have published recently, using our SVS and VarSeq software, and we love sharing their work with you. Congrats to all! Sebastian Mucha and Joanne Conington of Scotland’s Rural College along with colleagues collaboratively published Genome-wide association study of footrot in Texel sheep in Genetics Selection Evolution which used GWAS to investigate links between ovine footrot scores and molecular polymorphisms… Read more »

Recent Customer Publications

         April 2, 2015

Some of our customers have recently published using our SVS and VarSeq software in their studies. We wanted to share their work and congratulate everyone on their success! Maria Skerenova at the Institute of Clinical Biochemistry and her colleagues published Genetic variants in interleukin 7 receptor α chain (IL-7Ra) are associated with multiple sclerosis risk and disability progression in Central European… Read more »

Recent Customer Publications

         March 10, 2015

Several of our customers have published recently, using the SVS software and I wanted to share their work. Congrats to all! Daria Babushok and colleagues at The Children’s Hospital of Philadelphia published Emergence of Clonal Hematopoiesis in the Majority of Patients with Acquired Aplastic Anemia in the Cancer Genetics Journal which used comparative whole exome sequencing to evaluate clonal hematopoiesis in acquired aplastic… Read more »

Recent Customer Success

         February 19, 2015

A few of our customers have published recently and I would like to take the time to both recognize them for their achievement and pass on their articles. Enjoy! Kazima Bulayeva at the Vavilov Institute of General Genetics and her colleagues recently published Genomic Structural variants are linked with intellectual disability in the Journal of Neural Transmission. The paper looks at mutations… Read more »

Our customers’ success

         February 3, 2015

With January officially in the bag, 2015 is off to a great start, especially for some of our customers who have recently published. I wanted to take a minute to share them with you. Sander van der Laan at University Medical Center Utrecht, published Variants in ALOX5, ALOX5AP and LTA4H are not associated with atherosclerotic plaque phenotypes: The Athero-Express Genomics Study which assessed the impact of common variants… Read more »

Bridging the gap between genetics and organic chemistry at UIUC

         December 9, 2014

As Dr. Andreas Scherer mentioned in a blog post earlier this year, Golden Helix is committed to supporting the education of the next generation of genetic researchers. And as such, over the course of 2014, we at Golden Helix are working with education programs across the US and Canada to make teaching and learning bioinformatics easier. This fall semester at the… Read more »

Guest Post: Population Structure & Genetic Improvement in Livestock by Dr. Heather Huson

         July 30, 2014

Genetic improvement in livestock, particularly dairy cattle, has been a priority for both industry and researchers for nearly a century.  While the animal itself is the foundation for improvement, our research and the implementation of improvement has progressed with developing technologies and priorities.  In terms of genetics, we have evolved from basic measures of heritability to identifying specific mutations and… Read more »

Guest Post: Uncovering the Genetic Mechanisms of Common Language Disabilities, by John Eicher

         May 20, 2014

When many people think of learning disabilities such as dyslexia and language impairment, they typically do not think of a biological or medical condition. Even more rarely do people think of these conditions as being the result of biological and genetic phenomena. However, that is exactly what I have thought of every day during my doctoral training in the Department… Read more »

Matthew McClure, PhD Analyzes Genotypic Data to Determine Cattle’s Breeding Potential

         May 13, 2014

For lead geneticist Dr. Matthew McClure, of the Irish Cattle Breeding Federation (ICBF), finding a software program that could handle massive amounts of data as well as more than the standard twenty-three pairs of chromosomes found in humans was a challenge. McClure says, “Agriculture often feels like the black sheep of the genomics industry. The majority of current genetic analysis… Read more »

Guest Post: Finding Rare Pieces of Hay in a Haystack

         August 19, 2013

Utilizing Identical Twins Discordant for Schizophrenia to Uncover de novo Mutations We are living in exciting times – the reality of high-resolution Cand individual genome sequencing now offers renewed hope in the search for the causes of complex diseases. When this technology is combined with genetic relationships, individual sequences add unrivaled proficiency. Our lab is located in London, Ontario, Canada… Read more »

Vanessa Hayes, PhD and Desiree Petersen, PhD Use Population Genetics to Dig into Mankind’s Roots

         June 26, 2013

Humans are said to have a 0.1% rate of diversity, seemingly small, but actually quite significant when considering the future of personalized medicine. Gaining a deeper understanding of this genetic variance can help determine susceptibility to disease as well as medicinal response and outcomes. One-third of human genetic diversity can be found in a likely contender for the birthplace of… Read more »

Robert Kleta, MD, PhD and His Newly-Formed Team Publish in The New England Journal of Medicine in a Few Short Months with SVS

         May 16, 2013

Thirteen years ago, Dr. Robert Kleta had never heard of a genome-wide association study (GWAS), let alone considered doing one. Now, Dr. Kleta and his colleagues at the University College of London regularly publish articles in The New England Journal of Medicine and other journals on the genetics of rare diseases and their associated phenotypes. States Kleta, “For rare diseases,… Read more »

Dr. Folefac Aminkeng Saves Time and Increases Productivity with SVS to Study the Pharmacogenomics of Adverse Drug Reactions in Cancer Therapy

         October 17, 2012

Dr. Folefac Aminkeng is a Postdoctoral Fellow at The Centre for Molecular Medicine and Therapeutics (CMMT) at the University of British Columbia in Vancouver, BC, Canada. He utilizes GWAS studies to identify single-nucleotide polymorphisms (SNPs) that might be associated with serious adverse drug reactions (ADRs) in cancer therapeutics. The field of pharmacogenomics—how one’s genetic makeup affects drug response—has grown exponentially… Read more »

Peter K. Gregersen, MD Puts Analytical Power in the Hands of the Biologist with SVS

         August 21, 2012

Dr. Peter K. Gregersen, head of the Robert S. Boas Center for Genomics and Human Genetics at the Feinstein Institute for Medical Research, utilizes GWAS, targeted arrays, and sequencing technologies to identify genes associated with human autoimmune disorders. The arrival of the GWAS platform in the mid-2000’s greatly accelerated the pace of gene discovery—as well as accelerating the number of… Read more »

Dr. Ken Kaufman’s Webcast on Exome Sequencing Wildly Successful

         August 9, 2012

Thank you to everyone who joined us yesterday for a webcast by Dr. Ken Kaufman of Cincinnati Children’s Hospital: “Identification of Candidate Functional Polymorphism Using Trio Family Whole Exome DNA Data.” Over 750 people registered for this event and 430 attended – a new Golden Helix record! If you missed the webcast (or would like to watch it again), the… Read more »

“Easy-to-Use” SNP & Variation Suite Assists John Curtin, PhD in Uncovering Genetic Associations for Asthma and Allergies

         July 10, 2012

Dr. John Curtin is a Lecturer in Functional Genomics at the University of Manchester where he works with a large team studying the development of asthma in a birth cohort. This group has received data on study subjects periodically for over a decade including before birth. Given how much data there is, data management is a big deal to Dr…. Read more »

Agrigenomic Researcher at U.C. Davis, Gonzalo Rincon, DVM, and Colleagues Publish 14 Articles and Obtain 2 Patents Using SVS

         June 13, 2012

Editor’s Note: This case study was written while Dr. Gonzalo Rincon was with the University of California, Davis. Dr. Rincon is now working as a Principal Investigator in Animal Genetics at Zoetis. Gonzalo Rincon, DVM is a Project Scientist in the Medrano Lab, part of the Department of Animal Science, at the University of California, Davis. While the lab works… Read more »

Researcher Uses SVS for Pharmacogenetic Associations for 10 Years

         April 11, 2012

Dr. Julia Pinsonneault is a Research Scientist at The Ohio State University where she works to find biomarkers that guide effective treatment. Published recently in Neuropsychopharmacology, Julia has found success using SVS to find novel associations that move her research forward. Usually managing 3-5 research projects at a time from various cohorts, she found time in her busy schedule this… Read more »