Category Archives: Big picture

Concepts and Relevance of GWAS

         March 17, 2016
Genome-Wide Association Studies

Concepts and Relevance of Genome-Wide Association Studies Genome-Wide Association Studies continue to be a very effective method for determining the underlying cause of disease, Golden Helix is happy to share our long-standing knowledge with the community. We are very happy to announce that “Concepts and Relevance of Genome-Wide Association Studies”, a paper surrounding GWAS was recently published in Science Progress… Read more »

Scaling is in our DNA: Making Genomics Accessible

         February 11, 2016
Scalable Data

Scaling is in our DNA: Making Genomics Accessible One of the things I absolutely love about the work we do at Golden Helix is keeping up with the changes in data analysis driven by the iterative and generational leaps in technology. But one thing has always been a constant since day one: we break preconceived notions of what scale of… Read more »

Genetic Data Warehousing e-Book

         February 10, 2016
Genetic Data Warehouse

Genetic Data Warehousing e-Book In our webcast last week, we announced the upcoming release of VSWarehouse, a scalable genetic data warehouse for VarSeq. Genetic data warehousing becomes more important as Next-Generation Sequencing is taking off in the clinic, creating significant data management issues for clinicians, scientists and IT professionals alike. How can we retain the massive amounts of data coming out… Read more »

Announcing VSWarehouse – Golden Helix’s Data Warehouse Solution for genomic data

         January 21, 2016
VSWarehouse Updates

So, why are we launching a new data warehouse product? Why did we build VSWarehouse? According to Grand View Market Research, the next generation sequencing (NGS) market size was $2.0 billion (USD) globally in 2014. This number is expected to grow from 2015 to 2022 at an annual rate of about 40%. What drives this phenomenon is the increasing number… Read more »

What to expect from Golden Helix in 2016

         December 31, 2015
VSWarehouse

Golden Helix in 2016 We had a terrific year 2015. It was the year in which we got serious about the clinical testing market. We successfully continued on the path of attracting more referenceable clients such as University of Iowa, Baby Genes, Prevention Genetics and many more. We rounded out our VarSeq suite by adding more clinically relevant features and… Read more »

Happy Holidays!

         December 24, 2015
Happy Holidays

Like most, we at Golden Helix love this time of year! It is a time to spend with family and friends, creating memories and reflecting on the past year. From all of us here, to you and yours, we wish you a very happy holiday and a prosperous 2016!  

Announcing the 3rd Annual Abstract Challenge!

         December 21, 2015
Recent Customer Publications

As part of our ongoing commitment to empower genetic research, it is time to announce our third annual abstract challenge. Here at Golden Helix, we are dedicated to creating powerful software that enables researchers to complete complex analysis. This competition allows us to enable discovery by awarding software to those making an impact in the field. The competition has been very… Read more »

They’ve isolated the funding gene!

         November 3, 2015

Bipartisan Budget Act of 2015 Passed! We at Golden Helix, and I are certain that many in our community, are more than pleased to hear that President Obama has signed the “Bipartisan Budget Act of 2015“. Most importantly, the budget agreement raises discretionary spending by $80 billion in fiscal years 2016 and 2017 which should create room for increased spending… Read more »

What to know about VSReports

         October 27, 2015

What you need to know At the beginning of October, VSReports came to VarSeq. Since then, we have been getting rave reviews from our customers. As Dr. Andreas Scherer mentioned earlier this month, VSReports takes the output of your tertiary variant analysis and converts it into a fully customized and actionable clinical grade report in just one click. Additionally, VSReports ships with… Read more »

Reflection on ASHG 2015

         October 14, 2015

ASHG 2015 in Baltimore was a very good conference for us at Golden Helix. It was a delight to connect with existing clients as well as interested members of our community. The conference is a premium networking opportunity for professionals in our field, with an ever increasing number of talks, demos and a constantly expanding vendor exhibition area.    … Read more »

Top Five Add-On Scripts for SVS

         October 6, 2015

While stand-alone SVS is an amazing statistical software package for genomics analysis, adding additional Python scripts to the program can expand SVS’s genomic analysis capabilities. In this post, I’ll take you through the most frequently downloaded Add-On Scripts for SVS and the top five were not what I expected! Coming in at Number Five is the script Convert Dosages to… Read more »

Clinical Reporting comes to VarSeq

         September 17, 2015

The next release of VarSeq will ship a new product that is highly relevant to our customers in clinical testing labs. Via VSReports, VarSeq now has the ability to generate clinical-grade reports. These reports are fully customizable, containing focused and actionable data. VS Reports ships with report templates that are modeled off of the ACMG guidelines, the de-facto gold standard… Read more »

Precision Medicine e-Book

         September 15, 2015
e-Book

Precision Medicine e-Book “It’s far more important to know what person the disease has than what disease the person has.” – Hippocrates (460 BC – 370 BC) Almost 2,500 years ago, Hippocrates captured one of the key principles underlying precision medicine. In the 21st century we take the understanding of the individual characteristics of a person to a new level…. Read more »

The 10th Anniversary of GWAS

         July 30, 2015
10th Anniversary of GWAS

GWAS became possible about 10 years ago as the result of several scientific advances. Since then, GWAS has continually developed as a primary method for identification of disease susceptibility genes in humans and other organisms. At Golden Helix we are proud of our history in supporting GWAS analysis from its inception. Our software was used to analyze whole-genome data from… Read more »

Top 5 things you need to know about VSPipeline

         July 14, 2015

Recently, Golden Helix, Inc. announced the addition of VSPipeline to our VarSeq software suite. VSPipeline is a command-line interface that will allow high throughput environments the ability to tap the full power of VarSeq’s algorithms and flexible project template system from any command line context, including existing bioinformatics pipeline. So, what is the big deal? Here are the top five… Read more »

Partnership with MedGenome

         June 17, 2015

Just a few weeks ago we announced our partnership with MedGenome. The news was covered by a number of outlets including: Financial Express Pharmabiz Let me expIain the importance and impact of this announcement. Since Varseq was released, we have received strong interest from testing labs that are leveraging our product to implement cancer diagnostic pipelines. Please feel free to take… Read more »

VarSeq is a better ANNOVAR, snpEff and VEP

         June 9, 2015

Yes, I said it. “Them be fighting words” you may say. Well, it’s worth putting a stake in the ground when you have worked hard to have a claim worth staking. We have explored the landscape, surveyed the ravines and dangerous cliffs, laboriously removed the boulders and even dynamited a few tree stumps. Stake planted. Ok, so now I’m going… Read more »

Precision Medicine – Part VII – Regulatory Issues

         May 21, 2015
Regulatory Issues

Regulatory Issues Regulatory bodies such as the Federal Drug Administration (FDA) already have a full plate. In the US, FDA-regulated products account for 20 percent of each dollar spent by American consumers each year. More specifically, the work of the regulatory authorities include the following: Carefully considering benefits and risks when evaluating medical products Staying on top of rapidly advancing scientific innovations… Read more »