Variant analysis of 17 Supercentenarians whole genomes (14.5M input variants). The columns left to right are mutations not seen in any population catalog that are potentially damaging, those including variants up to 1% in population catalogs, variants annotated as Pathogenic in ClinVar that are very rare (<0.1% in 1000 genomes) and seen in a homozygous state, and finally Pathogenic variants not seen in any population catalog.

Leave a Reply

Your email address will not be published. Required fields are marked *