Tag Archives: Whole-genome imputation

To Impute, or not to Impute

      Golden Helix    February 5, 2015    No Comments on To Impute, or not to Impute

Genotype imputation is a statistical technique for estimating sample genotypes at loci that were not directly assayed by sequencing or microarray experiments.  There are several reasons why you might want to use imputation in a research study.  For example: Improve call rates in GWAS by imputing sporadic missing genotypes Harmonize the data content from different GWAS genotyping platforms so that… Read more »