Tag Archives: Sentieon

Getting Started Guide for Sentieon – Part II

Sentieon's Tools

Creating Custom Scripts The first part of the Getting Started Guide for Sentieon described the steps for downloading the Sentieon tools, acquiring a license file, and running the example script/pipeline to generate the VCF and BAM files. This blog will cover some custom script changes users can make to add more efficiency when running through multiple samples at once. We… Read more »

Getting Started Guide for Sentieon

Sentieon's Tools

Sentieon; your swift secondary analysis solution. Golden Helix’s software solutions present a reputable and top-quality analysis of your NGS data. Looking at this process from a 30,000 ft view, the annotation and filtering of variants in your vcf files and discovery of CNVs based coverage data in the bam file make up the tertiary level portion of the analysis. However,… Read more »

Exclusive Look at Sentieon TNscope Q&A

VS-CNV Annotations

Sentieon TNscope is a platform dedicated to the identification of tumor-normal somatic variants including single nucleotide variation (SNV), indel, as well as structure variations (SVs). In our recent webcast, Dr. Donald Freed, Bioinformatics Scientist at Sentieon, gave viewers an exclusive overview of the platform. The webcast generated a lot of great questions which I would like to share with you… Read more »

Sentieon’s Secondary Analysis Tools Explained

Sentieon's Tools

We find ourselves talking a lot about our partnership with Sentieon … and more specifically, extolling the powerful, comprehensive genomic data analysis solution we are now able to offer clients. Sentieon’s suite of secondary analysis tools made a significant improvement in runtime over BWA-MEM, GATK, Mutect, and MuTect2 while providing deterministic and identical results. Here are two fantastic white papers that… Read more »

Golden Helix announces Partnership with Sentieon

Partnership with Sentieon

Today, we are happy to announce a multi-year partnership with Sentieon, a company that develops bioinformatics secondary analysis tools to process genomic data. This partnership will integrate Sentieon’s secondary analysis tools with Golden Helix software to provide users with a comprehensive solution for genomic data analysis. Sentieon’s suite of secondary analysis tools made the significant improvement in runtime over BWA-MEM, GATK,… Read more »