A Hitchhiker’s Guide to Next Generation Sequencing – Part 2

When you think about the cost of doing genetic research, it’s no secret that the complexity of bioinformatics has been making data analysis a larger and larger portion of the total cost of a given project or study. With next-gen sequencing data, this reality is rapidly setting in. In fact, if it hasn’t already, it’s been commonly suggested that the… Read more »

Golden Helix Gives Away Over $60,000 in Software to Two Research Labs

This year at both IGES and ASHG, Golden Helix booth visitors filled out a short survey about their current and future work. In return, they were entered in a contest for a chance to win a one year SNP & Variation Suite server license with all modules (worth over $30,000!). We had over 230 people participate in the contest, and… Read more »

Recent Publications on Type 2 Diabetic Retinopathy, Grapevine Flavor, Pulminary Function, and Pharmacogenetics Testing

Let’s kick off this month’s recognition with Audrey Papp and Wolfgang Sadee at Ohio State University for their work on “Flavopiridol Pharmacogenetics: Clinical and Functional Evidence for the Role of SLCO1B1/OATP1B1 in Flavopiridol Disposition” just published in PLoS ONE. Audrey recently co-hosted a webcast with Golden Helix, check it out here. (All abstracts below.) Also in pharmacogenetics (albeit in mice)… Read more »

CNV Analysis Tips for Illumina Data

      Golden Helix    November 24, 2010    1 Comment on CNV Analysis Tips for Illumina Data

The following statement is representative of a common question that is posed to the Golden Helix support team: “I followed all of the steps in the SVS7 CNV analysis tutorial, but my results seem kinda funny. The segment means are skewed to the left and it doesn’t look like I have any copy number gains.  Can you tell me what… Read more »

A Hitchhiker’s Guide to Next Generation Sequencing – Part 1

If you have had any experience with Golden Helix, you know we are not a company to shy away from a challenge. We helped pioneer the uncharted territory of copy number analysis with our optimal segmenting algorithm, and we recently hand crafted a version that runs on graphical processing units that you can install in your desktop. So it’s probably… Read more »