Our webcast series for 2017 is starting off by giving the Golden Helix community their first look at our addition of genotype imputation into SVS! On Wednesday, January 11th, Gabe Rudy will discuss how users can now run their genotype phasing and imputation on human and animal data as part of their SVS analytics workflow.
Genotype imputation is a common component of many analytical workflows on microarray data.
At Golden Helix, we have worked hard over the years to make SNP & Variation Suite (SVS) a one-stop shop for all SNP-based large-N analytical workflows, and so it makes sense to add a robust and powerful genotype phasing and imputation engine. With the publication this year “Genotype Imputation with Millions of Reference Samples” in AJHG, the Brownings have demonstrated yet again the capabilities and performance of the Beagle algorithm package.
Join us in this webcast to see how we have written an open-source C++ port of Beagle v4.1 that is fully integrated into SVS and allows you to run your genotype phasing and imputation on human and animal data as part of your SVS analytics workflow.
In this webcast we will cover:
- Using the new SNP to Variant recoding feature to look up NGS alleles for existing micro-array data using dbSNP
- Using the 1000 Genomes Phase3 reference datasets for creating your own phased reference set for a set of samples genotyped or sequenced
- Running genotype imputation from SVS and examining the genotype and QC output for further downstream analysis
We hope you can join us for the unveiling of imputation in SVS!