We closed October with a record number of publications from our customers! Topics ranged widely from root traits in tropical maize to pretreatment depression severity. We hope you’ll enjoy reviewing some of our favorites:

• Bradley Aouizerat of NYU and colleagues published Human leucocyte antigen class I and II imputation in a multiracial population in the International Journal of Immunogenetics which considered the performance of two human leucocyte antigen gene dedicated imputation algorithms to determine imputation accuracy.
• Linda Reis and Elena Semina of the Medical College of Wisconsin, along with colleagues, published Analysis of CYP1B1 in pediatric and adult glaucoma and other ocular phenotypes in Molecular Vision. This study examined the CYP1B1 gene in 158 pediatric patients with primary congenital glaucoma and other ocular disorders to discover pathogenic variants.
• Genomic Regions Associated with Root Traits under Drought Stress in Tropical Maize was published in PLOS One by Raman Babu of CIMMYT and colleagues. In this study, the CIMMY Asia association mapping panel, which has 396 diverse tropical maize lines was phenotyped for various structural and functional traits of roots under different weather conditions.
• Michael Escamilla, Suzanne Gonzalez and colleagues from Texas Tech University Health Center published Replication of genome-wide association study (GWAS) susceptibility loci in a Latino bipolar disorder cohort in Bipolar Disorders which tested previously identified genetic variants associated with bipolar disorders in a sample of Latino subjects.
• A Preliminary Study of Genetic Variation in the Dopaminergic and Serotonergic Systems and Genome-Wide Additive Genetic Effects on Depression Severity and Treatment Response was published in Clinical Psychological Science by Rohan Palmer (then of Rhode Island Hospital) and colleagues. This study examined the “overlap in genetic effects between pretreatment depression severity and treatment response and the extent to which genetic effects could be attributed to variation in the dopaminergic and serotonergic systems”.
• Stan Nelson, Berit Kerner and Aliz Rao of UCLA and colleagues published Rare deleterious mutations are associated with disease in bipolar disorder families in Molecular Psychiatry which used exome sequencing to determine whether rare, damaging mutations share identity-by-descent in families with bipolar disorder could be associated with disease.

See a full list of publications citing our software here. If you don’t see your publication listed, please contact us at info@goldenhelix.com and we will be happy to add it!