Upcoming Webcast – Knowing Your Downstream: Functional Predictions


Presenter: Dr. Bryce Christensen, Statistical Geneticist and Director of Services
Date: Wednesday, May 15th, 2013
Time: 12:00 pm EDT

Next-Generation Sequencing analysis workflows typically lead to a list of candidate variants that may or may not be associated with the phenotype of interest. Any given analysis may result in tens, hundreds, or even thousands of genetic variants which must be screened and prioritized for experimental validation before a causal variant may be identified. To assist with this screening process, the field of bioinformatics has developed numerous algorithms to predict the functional consequences of genetic variants. Algorithms like SIFT and PolyPhen-2 are firmly established in the field and are cited frequently. Other tools, like MutationAssessor and FATHMM are newer and perhaps not known as well.

This presentation will review several of the functional prediction tools that are currently available to help researchers determine the functional consequences of genetic alterations. The biological principals underlying functional predictions will be discussed together with an overview of the methodology used by each of the predictive algorithms. Finally, we will discuss how these predictions can be accessed and used within the Golden Helix SNP & Variation Suite (SVS) software.

Register for this webcast »

Jessica Vionas

About Jessica Vionas

Jessica Vionas is the Director of Marketing at Golden Helix and as such, she is responsible for creating a comprehensive marketing, communications, and public relations strategy to position the company in the life sciences marketplace and ensure a consistently full sales funnel to meet and exceed revenue goals. Prior to joining Golden Helix in May of 2010, Jessica worked for eight years in the marketing department at a credit evaluation software company based in Bozeman. She received her Bachelor of Science in Sociology from Montana State University in 2006. When not at the office, Jessica enjoys playing with her dog Athena, reading marketing books, and spending time with her friends and family, preferably in the bright sunshine of Montana.
This entry was posted in News, events, & announcements. Bookmark the permalink.

Leave a Reply

Your email address will not be published. Required fields are marked *

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>